4-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-2-fluoro- - Names and Identifiers
4-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-2-fluoro- - Physico-chemical Properties
Molecular Formula | C11H13FN2O4
|
Molar Mass | 256.23 |
Density | 1.359±0.06 g/cm3 (20 ºC 760 Torr) |
Storage Condition | 2-8°C |
4-Pyridinecarboxylic acid, 5-[[(1,1-dimethylethoxy)carbonyl]amino]-2-fluoro- - Introduction
The chemical formula is C10H15FNO4. The following is a brief description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance and physical properties: Acid is white crystal or crystalline powder.
2. Solubility: The compound can be dissolved in water and organic solvents (such as methanol, ethanol, etc.), but insoluble in Ether solvents.
Use:
Acid is commonly used in fluorination reactions in organic synthesis as a fluorinating agent and reagent for introducing fluorine atoms.
Method:
Acid can be synthesized by a variety of methods, one of the commonly used methods is the esterification reaction of pentafluorothiosulfonamide (TBSF) and 2-aminoisopropanol ester (tert-Boc-2-amino-1-propanol), and converted to the desired product in the presence of potassium carbonate.
Safety Information:
1. Acid is a chemical and should be stored in a dark, dry and well-ventilated place.
2. Use or operation should wear appropriate personal protective equipment, such as gloves and protective glasses.
3. Avoid inhaling the dust or vapor of the compound and avoid skin contact or ingestion.
4. If skin contact or inhalation occurs, rinse immediately with plenty of water and seek medical attention in time.
Please note that the information provided above is for reference only. In practical applications, corresponding safety measures must be taken according to specific conditions and experimental requirements, and relevant operating procedures and regulatory requirements must be followed.
Last Update:2024-04-10 22:29:15